Yes - Body temperature has an effect on blood loss. Hypothermia affects haemostasis.
One of the most widely documented effects of hypothermia is coagulopathy. Hypothermia affects haemostasis on several levels:
Early animal studies have shown that hypothermia causes reversible platelet sequestration in the liver and spleen. Hypothermia also directly affects platelet function by decreasing production of thromboxane B2 and expression of platelet surface molecules.
When clotting assays are performed at temperatures below 37°C, the results are significantly prolonged. Prothrombin time is significantly increased at temperatures below 35°C, and activated partial thromboplastin time is similarly prolonged at temperatures below 33°C. In contrast, when clotting tests using blood from hypothermic rats are performed at 37°C, no significant abnormalities are seen. This suggests that the major mechanism of hypothermia-induced coagulopathy results from altered enzymatic activity. In fact, at 33°C the clotting process is functionally equivalent to having a 33% factor-IX deficiency, even in the presence of normal clotting factor levels. These effects are directly reversible with the correction of hypothermia, emphasizing the importance of maintaining normal core temperatures in injured patients.
Fibrinolysis is increased in hypothermic animals, and is felt to be as a result of impaired inhibitors of clot lysis, such as plasminogen activator inhibitor or alpha-2-antiplasmin. In the clinical setting, the trauma patient’s coagulation profile may be reported as normal, as the sample is usually heated to 37°C in the laboratory before it is tested.
Hypothermia in the trauma patient; Injury, Volume 35, Issue 1, January 2004, Pages 7-15; Betty J. Tsuei and Paul A. Kearney
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