Results 1 to 2 of 2

Thread: Trial results HBOC's

  1. #1
    Registered User
    Join Date
    Dec 2004

    Trial results HBOC's

    I'm curious to know of any updates on the trial results of Hemoglobin-based Oxygen carriers that have been tested. I'm sure they have improved but, have they been accepted as safe to be used in general practice ?

  2. New Feature! NoBlood Answers!

    • ASK questions regarding Transfusion Alternatives and Patient Blood Management.
    • SHARE your facts, opinions and personal experience.
    • DISCOVER the best answers chosen by Healthcare Professionals and the Public.
    • RANK the best answers.

    Click here to see the Best Answers to Top Questions.

  3. #2


    HBOC-201 was found safe in large phase III Trial so says Denise Grady in Health Day News published June 20,2008.

    Look it up in the June issue of the Journal of Trauma: Injury, Infection, and Critical Care.

    She wrote that patients could receive up to 10 units of the substitute or unlimited blood transfusions otherwise. The article spoke of 688 patients 18 years old and up, receiving elective orthopedic surgery.

    They were evaluated daily and 6 weeks after the surgery.

    It is a hemoglobin based oxygen carrier.

    I didn't read the article but it should be noted that once the 10 unit threshold is reached with blood transfusions, there is a 50% mortality. Are there any studies looking at bloodless statistics?

    Anecdotally, none of my patients have died, ever. The patient with the lowest count was 2.9 and the average low looking at the numbers below 5.5 (the oxy hgb dissociative curve) was about Hgb 4.5. More women than men.

    Oh yea, none of the hospitals I worked in were bloodless either, just wonderful and caring doctors. Well, a couple with bad attitudes but still wonderful and probably deep down somewhere caring or they would not have taken on the patients and succeeded.

Similar Threads

  1. HBOC availibility
    By jabriol in forum Ask a Professional
    Replies: 12
    Last Post: 04-05-2009, 10:49 AM
  2. Trial results HBOC's
    By martyj2 in forum Ask a Professional
    Replies: 1
    Last Post: 01-06-2009, 11:20 AM
  3. Results of Blood Substitute Trial Show No Survival Advantage to Trauma Patients
    By Tony Paskitti in forum News and Hot Topics such as Hepatitis C, SARS and AIDS
    Replies: 5
    Last Post: 11-14-2007, 10:51 AM
  4. Results of major hepatectomy without vascular clamping . . .
    By Sharon Grant in forum Medical Articles and Abstracts
    Replies: 0
    Last Post: 07-13-2007, 09:02 PM
  5. HBOC's
    By Charles Needham in forum General Discussions
    Replies: 2
    Last Post: 07-10-2006, 10:23 PM

Tags for this Thread


Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts