a friend of mine recently suffered ARDS as a complication of sepsis. he was admitted to the intensive care unit; after a few days he appeared to be responding to the antibiotics he was on. however, he was given 2 units of packed cells on one occasion and another two units a few days later. unfortunately, he took a turn for the worse and died. i was wandering if he should have been given blood transfusions at all, given that they can cause TRALI which in turn leads to ARDS, which he already was suffering from.